Possible acetaminophen poisoning complicated by puerperal sepsis

Acetaminophen Poisoning

Acetaminophen is one of the most popular nonnarcotic analgesic–antipyretic agents available. Inappropriate use of this agent can lead to significant morbidity and mortality secondary to hepatic necrosis. Several patient-specific factors impact its metabolism and the subsequent production of its toxic metabolite when consumed in excess. Rapid diagnosis and treatment with N-acetylcysteine in the ...

Puerperal Sepsis: A Review

The Prevention of Puerperal Sepsis.

Intestinal obstruction due to a gall-stone is rare, but in 1914 Wagner16 collected 334 cases. The patients are usually fat women over 50 years of age, females being five times more numerous than male sufferers. The onset is sudden with vomiting, and at first pain and collapse are not prominent. The intestine, though obstructed, is not strangulated, as in a hernia, and since its vascular supply ...

Acetylcysteine for acetaminophen poisoning.

This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author’s clinical r...

Irregular Manifestations of Puerperal Sepsis